Neoadjuvant therapy is employed before the primary treatment of sarcomas. It is not uncommon that it fails due to multi-drug resistance gene causing unnecessary delays in surgery. Tc-99m MIBI, a radiopharmaceutical, is taken-up in these tumours. Being substrate of P-glycoprotein (Pgp), its washout from the malignant tissue may predict the response of sarcoma to neoadjuvant therapy. This book presents the author¿s experience of in-vivo quantitative estimation of the washout rates of Tc-99m MIBI from nuclear medicine scans of various bone and soft-tissue sarcomas. These rates were then assessed for their ability to predict the effectiveness of neoadjuvant therapy initiated afterwards.
| Autorius: | Muhammad Sohaib |
| Leidėjas: | LAP LAMBERT Academic Publishing |
| Išleidimo metai: | 2014 |
| Knygos puslapių skaičius: | 80 |
| ISBN-10: | 3659580503 |
| ISBN-13: | 9783659580505 |
| Formatas: | 220 x 150 x 5 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Washout Rate of Tc-99m MIBI in Bone and Soft-tissue Sarcomas: Is it a predictor of Tissue Necrosis caused by Neoadjuvant Therapy?“
