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The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
Serija: | Handbook of Experimental Pharmacology |
Leidėjas: | Springer Nature Switzerland |
Išleidimo metai: | 2023 |
Knygos puslapių skaičius: | 328 |
ISBN-10: | 3031384369 |
ISBN-13: | 9783031384363 |
Formatas: | 241 x 160 x 23 mm. Knyga kietu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease“