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Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF-~ in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF-~ was first isolated and characterized as a dimeric pep tide from both human and bovine sources (1-3), but the entire fieldofTGF-~ research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF-~ does not playa central role in embryonic differentiation or in adult function, and furthermore, malfunction of the normal physiologyofTGF-~can have disastrous consequences in almost all ofthese sites. Therefore, the present comprehensive review of so many aspects ofTGF-~ function is a most welcome attempt to bring together a huge body of experimental data that is of the utmost importance in the field of oncology.
Serija: | Cancer Drug Discovery and Development |
Leidėjas: | Humana Press |
Išleidimo metai: | 2008 |
Knygos puslapių skaičius: | 764 |
ISBN-10: | 1588297144 |
ISBN-13: | 9781588297143 |
Formatas: | 260 x 183 x 46 mm. Knyga kietu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology“