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DNA delivery into cells is a rapidly developing area in gene therapy and biotechnology. Moreover, it is a powerful research tool to determine gene structure, regulation, and function. Viral methods of DNA delivery are well-characterized and efficient, but little is known about the toxicity and immunogenecity of viral vectors. As a result, non-viral, transfection methods of DNA delivery are of increasing interest. Synthetic DNA Delivery Systems is a comprehensive and current resource on DNA transfection. The use of histidine-rich peptides and polypeptides as DNA delivery systems and self-assembled delivery systems based on cationic lipids and polymers are discussed. Targeted delivery to organelles, tumor cells and dendritic cells comprise an important topic.
| Serija: | Biotechnology Intelligence Unit |
| Leidėjas: | Springer US |
| Išleidimo metai: | 2003 |
| Knygos puslapių skaičius: | 152 |
| ISBN-10: | 0306477017 |
| ISBN-13: | 9780306477010 |
| Formatas: | 241 x 160 x 13 mm. Knyga kietu viršeliu |
| Kalba: | Anglų |
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