Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized.Diphenylamine-2,4`-dicarboxylic acid [1] is obtained in a high yield by refluxing a mixture of 4-aminobenzoic acid and 2-chloro benzoic acid in the presence of catalytic amount of copper oxide. 9(10H)-Acridone-2-carboxylic acid [2] is synthesized in ring closure reaction by heating compound [1] in sulfuric acid followed by basic hydrolysis.Reaction of compound [2] with thiosemicarbazide in the presence of phosphorus oxychloride gave 2-[5-amino-1, 3, 4-thiadiazole-2-yl]-9(10H)-acridone
Autorius: | Ayad Hameed, Emad Yousif, Ayad Kreem, |
Leidėjas: | LAP LAMBERT Academic Publishing |
Išleidimo metai: | 2011 |
Knygos puslapių skaičius: | 88 |
ISBN-10: | 384432786X |
ISBN-13: | 9783844327861 |
Formatas: | 220 x 150 x 6 mm. Knyga minkštu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „SYNTHESIS OF COMPOUNDS CONTAINING 9(10H)-ACRIDONE: SYNTHESIS OF SOME NEW HETEROCYCLIC COMPOUNDS CONTAINING 9(10H)-ACRIDONE, AND STUDYING THEIR BIOLOGICAL ACTIVITY“