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One of the major problems associated with this drug is its low aqueous solubility, which results into poor bioavailability after oral administration. Oral bioavailability of a drug depends on its solubility and dissolution rate, it indicates that dissolution is the rate determining step for the drug. Various techniques of solubility enhancement are most promising approach for improving the solubility. Most of the drugs being discovered are lipophilic in nature and have poor aqueous solubility, thereby posing problem in formulation as delivery system. Due to which many products are unable to show their full potential. Solubility enhancement techniques are useful to improve the release rate and bioavailability of poorly soluble drugs in plasma.
| Autorius: | Ms. Urvashi Sharma, Ashok Koshta, Neetesh Jain, |
| Leidėjas: | LAP LAMBERT Academic Publishing |
| Išleidimo metai: | 2020 |
| Knygos puslapių skaičius: | 80 |
| ISBN-10: | 6202526920 |
| ISBN-13: | 9786202526920 |
| Formatas: | 220 x 150 x 5 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Solubility Enhancement of Poorly Aqueous Soluble Drug: Solubility Enhancement“
