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This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.
Serija: | Resistance to Targeted Anti-Cancer Therapeutics |
Leidėjas: | Springer Nature Switzerland |
Išleidimo metai: | 2017 |
Knygos puslapių skaičius: | 164 |
ISBN-10: | 3319561960 |
ISBN-13: | 9783319561967 |
Formatas: | 241 x 160 x 15 mm. Knyga kietu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Resistance to Molecular Therapies for Hepatocellular Carcinoma“