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In this present study, antioxidant potential of the methanol extract of the root of Cajanus cajan Linn (MCC¬R) was identified by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, Reducing power assay, total antioxidant activity test and also by total Phenolic content test. In DPPH scavenging assay the IC¬50 value of the extract was found to be 17.44¿g/ml while the IC¬50 value of the reference standard ascorbic acid was 15.06 ¿g/ml.Total antioxidant capacities of MCC¬R is expressed as the number of equivalent of ascorbic acid 266.7mg/g and the reducing power of MCC¬R increased with concentration of the sample. The amount of total Phenolic 262.31mg/g Gallic acid. These results suggest that the MCC¬R providing potent antioxidant properties and offering effective protection from free radicals. Form this view point, MCC¬R were tested for oral glucose tolerance test (OGTT) in normal mice. The postprandial blood glucose lowering effects of MCC¬R (400mg/kg) were compared to a known type 2 diabetes drug (Acarbose-50mg/kg). The MCC¬R were also tested alloxan (120 mg/kg) induced diabetic mice for 7 days.The blood glucose lowering effects MCC¬¬¬¬¬R (200mg/kg).
| Autorius: | Faisal Ahmed, Razib Ghose, Shikder Tairin Hossain Urmi, |
| Leidėjas: | LAP LAMBERT Academic Publishing |
| Išleidimo metai: | 2013 |
| Knygos puslapių skaičius: | 52 |
| ISBN-10: | 365937508X |
| ISBN-13: | 9783659375088 |
| Formatas: | 220 x 150 x 4 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Pharmacology: Antioxidant and Antidiabetic Activity“
