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One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays

-22% su kodu: BOOKS
132,12 
Įprasta kaina: 169,38 
-22% su kodu: BOOKS
Kupono kodas: BOOKS
Akcija baigiasi: 2025-03-10
-22% su kodu: BOOKS
132,12 
Įprasta kaina: 169,38 
-22% su kodu: BOOKS
Kupono kodas: BOOKS
Akcija baigiasi: 2025-03-10
-22% su kodu: BOOKS
2025-03-31 132.12 InStock
Nemokamas pristatymas į paštomatus per 11-15 darbo dienų užsakymams nuo 20,00 

Knygos aprašymas

This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients¿ primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine.

In this thesis, the author firstly describes the need and concept of ¿partipetting¿ for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, andrealization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.

Informacija

Autorius: Seo Woo Song
Serija: Springer Theses
Leidėjas: Springer Nature Singapore
Išleidimo metai: 2020
Knygos puslapių skaičius: 76
ISBN-10: 9811380961
ISBN-13: 9789811380969
Formatas: 235 x 155 x 5 mm. Knyga minkštu viršeliu
Kalba: Anglų

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