Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.
| Serija: | Contemporary Immunology |
| Leidėjas: | Humana Press |
| Išleidimo metai: | 2013 |
| Knygos puslapių skaičius: | 732 |
| ISBN-10: | 1475756860 |
| ISBN-13: | 9781475756869 |
| Formatas: | 254 x 178 x 40 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
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