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This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.
| Serija: | Advances in Neurobiology |
| Leidėjas: | Springer International Publishing |
| Išleidimo metai: | 2018 |
| Knygos puslapių skaičius: | 292 |
| ISBN-10: | 3319842870 |
| ISBN-13: | 9783319842875 |
| Formatas: | 235 x 155 x 16 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Leucine-Rich Repeat Kinase 2 (LRRK2)“
