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Based on the regio and stereoselectivity of 1,3-dipolar cycloaddition reactions of nitrones to alkenes the book has focus on - regio and stereoselectivity synthesis of N-nucleosides by 1,3-dipolar cycloaddition of sugar-derived nitrones with N-arylmaleimides. - 1,3-Dipolar cycloaddition of N-ribosylnitrones and N-arylmalaimides affords anti-isoxazolidine. - A series of novel nitrones were prepared and isolated in a pure state, and they cycloadded to some allyl derivatives to give isoxazolidine derivatives and studied the stereoselectivity of their cycloaddition reactions. - Lewis acid (MgBr2.Et2O) was applied as a catalyst for 1,3-dipolar cycloaddition reactions and it highly effect the rate of cycloaddition reaction. - we studied also the biological activity of nitrone and isoxazolidine compounds.
| Autorius: | Mohammed Al-Ghorbani, Usama Al-Timari, Taha Abu Bakr Fathl, |
| Leidėjas: | Noor Publishing |
| Išleidimo metai: | 2016 |
| Knygos puslapių skaičius: | 124 |
| ISBN-10: | 3330798343 |
| ISBN-13: | 9783330798342 |
| Formatas: | 220 x 150 x 8 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Isoxazolidine derivatives: Synthesis and biological ¿activity study“
