Cyclodextrins have the ability to solubilize hydrophobic drugs by providing a conical cavity to encapsulate it and hence used for drug delivery. So it is interesting to study the interaction of an anti cancer agent i.e.; gallic acid with cyclodextrin in aqueous media. Different physico-chemical properties such as density, viscosity are used as tools to study the interactions. Uv-spectroscopic study establishes formaion of 1:1 inclusion complex. Various results reveal that the solutions are characterized predominantly by solute -solvent interactions and gallic acid behaves as a long-range structure maker.
Autorius: | Abhijit Sarkar, Biswajit Sinha, |
Leidėjas: | LAP LAMBERT Academic Publishing |
Išleidimo metai: | 2017 |
Knygos puslapių skaičius: | 56 |
ISBN-10: | 333004442X |
ISBN-13: | 9783330044425 |
Formatas: | 220 x 150 x 4 mm. Knyga minkštu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Interactions between an anticancer agent and cyclodextrin: Inclusion complex formation and solution thermodynamics“