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Vitiligo, also known as leukoderma, is an acquired de-pigmentary disorder characterized by the appearance of white patches resulting from the loss of functional melanocytes and melanin from the skin with worldwide prevalence of approximately 0.1 to 8%. It most often affects the face, elbows and knees, hands and feet, and genitals and is more noticeable in darker-skinned people because of the contrast of white patches against dark skin. The exact etiopathophysiology of Vitiligo is not clearly known, but some main theories exist to explain it: the autoimmune hypothesis, the neural hypothesis, the self-destruct hypothesis (auto cytotoxic), biochemical, oxidative stress, melano-cytorrhagy, and decreased melanocyte survival hypotheses. different treatment modalities of vitiligo like steroidal treatment, chemo-phototherapy, vitamin D analogues, pseudo catalase, vitamin B12, surgical therapy and herbal treatments. Although, there are numerous medical and surgical interventions available to treat vitiligo, there is no study showed a definite treatment measure.Therefore, more randomized controlled trials on the treatment of vitiligo are necessary.Keywords: Vitiligo, Autoimmunity, Melanocyte
| Autorius: | Abdisa Hunduma, Vijender Singh, Vijeta Gupta, |
| Leidėjas: | LAP LAMBERT Academic Publishing |
| Išleidimo metai: | 2020 |
| Knygos puslapių skaičius: | 68 |
| ISBN-10: | 6202803576 |
| ISBN-13: | 9786202803571 |
| Formatas: | 220 x 150 x 5 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Impact of pharmaceutical care in management and treatment of Vitiligo“
