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Since the 1970s, there has been much discussion about the ¿glucoreceptor¿ and ¿substrate site¿ and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the ¿glucoreceptor theory.¿ This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells.The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: ¿glucoreceptor theory¿. Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
| Leidėjas: | Springer-Verlag GmbH |
| Išleidimo metai: | 2018 |
| ISBN-10: | 9811300011 |
| ISBN-13: | 9789811300011 |
| Formatas: | 241 x 160 x 10 mm. Knyga kietu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Glucose-sensing Receptor in Pancreatic Beta-cells“
