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This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Autorius: | Arseniy E. Yuzhalin, Anton G. Kutikhin, |
Leidėjas: | Birkhäuser Basel |
Išleidimo metai: | 2013 |
Knygos puslapių skaičius: | 200 |
ISBN-10: | 3034806876 |
ISBN-13: | 9783034806879 |
Formatas: | 241 x 160 x 17 mm. Knyga kietu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Genomics of Pattern Recognition Receptors: Applications in Oncology and Cardiovascular Diseases“