The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist¿s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound¿s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop
| Serija: | AAPS Advances in the Pharmaceutical Sciences Series |
| Leidėjas: | Springer International Publishing |
| Išleidimo metai: | 2018 |
| Knygos puslapių skaičius: | 796 |
| ISBN-10: | 3319826182 |
| ISBN-13: | 9783319826189 |
| Formatas: | 235 x 155 x 43 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Formulating Poorly Water Soluble Drugs“
