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A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. PKC isozymes are activated by a variety of hormones, such as adrenalin and angiotensin, by growth factors, including epidermal growth factor and insulin, and by neurotransmitters such as dopamine and endorphin; these stimulators, when bound to their respective receptors, activate members of the phospholipase C family, which generates diacylglycerol, a lipid derived second messenger.
Autorius: | Eman Refaat, Amr Mahmoud MM Ibrahim, |
Leidėjas: | LAP LAMBERT Academic Publishing |
Išleidimo metai: | 2018 |
Knygos puslapių skaičius: | 76 |
ISBN-10: | 6137347613 |
ISBN-13: | 9786137347614 |
Formatas: | 220 x 150 x 5 mm. Knyga minkštu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Carcinogenesis and Protein Kinase C“