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Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.
| Autorius: | Florian Hahne, Seth Falcon, Robert Gentleman, Wolfgang Huber, |
| Serija: | Use R! |
| Leidėjas: | Springer New York |
| Išleidimo metai: | 2008 |
| Knygos puslapių skaičius: | 300 |
| ISBN-10: | 0387772391 |
| ISBN-13: | 9780387772394 |
| Formatas: | 235 x 155 x 19 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
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