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In this revised and expanded second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome c, and caspases), the direct assessment of the role of pro-apoptotic proteins in neurons by viral infections and microinjections, and the detection of pro-apoptotic proteins in situ. There are also hands-on methods for the study of apoptosis mechanisms in neuronal compartments, for studying synaptosis, and for establishing gene expression profiles in neurodegenerative brain tissues by using DNA microarrays.
Serija: | Neuromethods |
Leidėjas: | Humana Press |
Išleidimo metai: | 2002 |
Knygos puslapių skaičius: | 268 |
ISBN-10: | 1588290123 |
ISBN-13: | 9781588290120 |
Formatas: | 241 x 160 x 20 mm. Knyga kietu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Apoptosis Techniques and Protocols“