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Propolis was extracted with methanol and the concentrated extract was then partitioned with pet-ether,carbon tetrachloride and chloroform and ethyl acetate.The Ethyl acetate extract of Propolis were subjected to free radical scavenging activity by the method of Brand-Williams et al., 1995. Here, tert-butyl-1-hydroxytoluene (BHT) was used as reference standard. In this investigation Propolis showed moderate free radical scavenging activity with the IC50 value of 220 ¿g/ml.The Ethyl acetate extract of propolis were subjected to antimicrobial screening at a dose 400 ¿g/disc. The crude extract showed mild antimicrobial activity with average zone of inhibition 7-8 mm.The extract was further subjected to brine shrimp lethality test.It showed cytotoxicity with a considerable potency. The LC50 value of the ethyl acetate extract of propolis was found to be 1.089 ¿g/ml.
| Autorius: | Md. Yousuf Ali, Utpal Kumar Mondal, |
| Leidėjas: | LAP LAMBERT Academic Publishing |
| Išleidimo metai: | 2012 |
| Knygos puslapių skaičius: | 92 |
| ISBN-10: | 3659304875 |
| ISBN-13: | 9783659304873 |
| Formatas: | 220 x 150 x 6 mm. Knyga minkštu viršeliu |
| Kalba: | Anglų |
Parašykite atsiliepimą apie „Antioxidant, Antimicrobial and Toxicological Investigation of Propolis: Pharmacological evaluation of Propolis collected from Sudarbans“
