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This book is focused on the development of non-steroidal anti-inflammatory drugs (NSAIDs); the biological target of these drugs is cyclooxygenase (COX) enzyme, which exists in two closely related isoforms viz. COX-1and COX-2. Based on the housekeeping functions of COX-1isoform and pathophysiological roles COX-2 isoform, the selective inhibition of COX-2 is desirable. NSAIDs like aspirin, ibuprofen, indomethacin, diclofenac, celecoxib, rofecoxib etc. exert their anti-inflammatory effects through the selective/non-selective inhibition of COX-1and/or COX-2 enzymes.
Autorius: | Atul Bhardwaj, Jatinder Kaur, |
Leidėjas: | LAP LAMBERT Academic Publishing |
Išleidimo metai: | 2012 |
Knygos puslapių skaičius: | 72 |
ISBN-10: | 3848498936 |
ISBN-13: | 9783848498932 |
Formatas: | 220 x 150 x 5 mm. Knyga minkštu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Advances in Anti-Inflammatory Drug Research: Various efforts made towards the development of anti-inflammatory drugs“