Advanced Medicinal Chemistry: A Laboratory Guide

Although some practical manuals are available for understanding different aspects of Medicinal Chemistry, none of them covers broadly. This necessitated the authors to compile "Advanced Medicinal Chemistry - A Practical Guide" to suit the requirements of postgraduate (PG) students of pharmaceutical chemistry, pharmaceutical analysis, quality assurance, pharmacognosy, phytochemistry. It is useful to PG students of chemistry, biotechnology and allied fields too. A sincere effort has been made to cover all aspects of Medicinal Chemistry in a comprehensive manner such as: isolation of active ingredients from natural sources including the current extraction techniques (Part A); purification and drying of solvents (Part B); details of synthesis of drugs and drug intermediates like synthetic procedure, reaction mechanism, retrosynthetic analysis, physical properties, uses, along with references (Part C); analytical methods of active pharmaceutical ingredients (APIs) in different formulations (Part D); oil and fat analysis (Part E). Further Part F offers the readers to train themselves in interpreting UV, IR, NMR, Mass spectra while Part G emphasizes on the essentials of bioinformatics and molecular modeling, the backbone for drug design. Contents Part A: Isolation of natural products of Medicinal interest, Part B: Solvent purification techniques, Part C: Synthesis of drug intermediates and Drug candidates, Part D: Quantitative estimation of Drugs / API's in formulations, Part E: Analysis of oils and fats, Part F: Interpretation of different spectra, Part G: Essentials of bioinformatics and Molecular modeling