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Actin is a ubiquitous protein present in high concentrations in virtually all cells. It's assembly and disassembly is modulated by more than 100 actin-binding proteins. These interactions are essential for a variety of important cellular processes including cell division, gene expression and motility. There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders. This volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole. Additionally, clinicians will be interested because the book explains the role of cytoskeletal proteins in various diseases, including cancer and immune system disorders.
Serija: | Protein Reviews |
Leidėjas: | Springer US |
Išleidimo metai: | 2010 |
Knygos puslapių skaičius: | 384 |
ISBN-10: | 1441924531 |
ISBN-13: | 9781441924537 |
Formatas: | 235 x 155 x 21 mm. Knyga minkštu viršeliu |
Kalba: | Anglų |
Parašykite atsiliepimą apie „Actin-Binding Proteins and Disease“